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Pregnancy and Birth to 24 Months Systematic Review

Systematic Review Question

What is the relationship between shorter versus longer durations of any human milk feeding and cardiovascular disease outcomes in offspring?

Conclusion Statement

Moderate evidence suggests that there is no association between the duration of any human milk feeding and blood pressure in childhood.

Evidence about the relationship of shorter versus longer durations of any human milk feeding with blood lipids in childhood and adulthood and with metabolic syndrome was inconclusive, and there was insufficient evidence to determine the relationship of shorter versus longer durations of any human milk feeding with endpoint cardiovascular disease outcomes, blood pressure in adolescence or adulthood, blood lipids in adolescence, and arterial stiffness. 

Grade: Moderate – blood pressure in childhood; Grade Not Assignable – cardiovascular disease, cardiovascular disease-related mortality, blood lipids, blood pressure in adolescence or adulthood, arterial stiffness, metabolic syndrome