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Pregnancy and Birth to 24 Months Systematic Review

Systematic Review Question

What is the relationship between never versus ever feeding human milk and childhood leukemia?

Conclusion Statement

Limited evidence suggests that never versus ever being fed human milk is associated with a slightly higher risk of childhood leukemia. The evidence comparing never being fed human milk with being fed human milk for short durations (i.e., < 6 months) and risk of childhood leukemia is mixed. However, the evidence comparing never being fed human milk with being fed human milk for long durations (i.e., ≥ 6 months) is mostly consistent and is associated with a slightly higher risk of childhood leukemia

Grade: Limited