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2010 Dietary Guidelines Advisory Committee Systematic Reviews

Systematic Review Question

What effect has folic acid fortification policy had on serum folate, plasma, and red blood cell folate status of US and Canada women, men, and children?

Conclusion Statement

Strong and consistent evidence demonstrates serum, plasma and red blood cell (RBC) folate concentrations have increased in the United States and Canada, following mandatory folate fortification.

2010 DGAC Grade: Strong